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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12729 | RIPK1-IN-3 | Others | |
RIPK1-IN-3 is a RIPK1 inhibitor, with anti-inflammatory proprieties. | |||
T9095 | Necrostatin-34 | 2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4 | RIP kinase |
Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain. | |||
T81268 | RIPK1-IN-17 | RIP kinase | |
RIPK1/3-IN-1 (Compound 10) is a selective inhibitor of both RIPK1 and RIPK3, effectively preventing necroptosis by blocking the phosphorylation of RIPK1, RIPK3, and MLKL [1]. |